Brainstem pathology in amyotrophic lateral sclerosis and primary lateral sclerosis: A longitudinal neuroimaging study
نویسندگان
چکیده
منابع مشابه
Neuroimaging in amyotrophic lateral sclerosis.
To cite: Toro J, Reyes S, Useche N. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013201416 DESCRIPTION A 54-year-old man presented with a 4-month history of gait difficulty and progressive leg weakness, predominantly on the left side. A neurological examination revealed slurred speech, tongue fasciculations, spastic weakness and hyperreflexia of both lower ext...
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Magnetic resonance imaging measures have been proposed as objective markers to study upper motor neuron loss in motor neuron disorders. Cross-sectional studies have identified imaging differences between groups of healthy controls and patients with amyotrophic lateral sclerosis (ALS) or primary lateral sclerosis (PLS) that correlate with disease severity, but it is not known whether imaging mea...
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Amyotrophic lateral sclerosis (ALS) is characterized by neuro-ophthalmological abnormalities beyond disturbed oculomotor control such as decreased visual acuity and disturbed visual evoked potentials. Here we report retinal alterations in a cohort of 24 patients with clinically definite (n = 20) or probable (n = 4) ALS as compared to matched controls. High-resolution spectral domain optical coh...
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OBJECTIVE The prominent histopathological feature of the amyotrophic lateral sclerosis (ALS) is the presence of intracellular inclusions in degenerating neurons and their axons. The appearance and localization of these pathological structures depend on an aggregated protein that forms their scaffold. We investigated if γ-synuclein, an aggregation-prone protein highly expressed in healthy motor ...
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Behçet’s disease is a multisystem vasculitis. Its neurological involvement mostly includes parenchymal and non-parenchymal central nervous system manifestations. Peripheral nervous system presentations are rare. A 32-yr-old male patient who fulfilled the international study group criteria for Behçet’s disease, referred to our center with walking difficulty and repeated falling downs. Neurologi...
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ژورنال
عنوان ژورنال: NeuroImage: Clinical
سال: 2019
ISSN: 2213-1582
DOI: 10.1016/j.nicl.2019.102054